Does insulin resistance cause weight gain? This article outlines the current view on the causes and progression of type 2 diabetes and explores the work of Newcastle University Professor Roy Taylor and Peter Attia. Professor Roger Unger’s prize-winning lecture is also discussed. It is important to follow a healthy diet and moderate physical activity. Regular moderate-intensity physical activity increases muscle insulin sensitivity and improves glucose energy use. Even just one session of moderate exercise increases glucose uptake by 40%.
Current view on the pathway to type 2 diabetes
There are two main theories regarding the cause of type 2 diabetes. One proposes that insulin resistance is a result of an increase in the consumption of carbohydrates, which then promotes the body’s inability to use insulin properly, and the other suggests that obesity is the root cause of the disease. In any case, both theories are far from being completely correct, as they require further study to establish their respective causes and consequences.
Insulin resistance may be complex and may occur as a result of genetic defects combined with environmental stresses, such as infections and obesity. Regardless, insulin resistance must lead to impaired signal transduction and glucose uptake in the cells. However, if b-cells are a direct cause of type 2 diabetes, their dysfunction may prove critical. In either scenario, insulin resistance may be associated with a decrease in glucose-regulated insulin secretion.
A mutation in the insulin receptor gene causes a person to become insulin-resistant. In some cases, a mutant allele may interfere with the normal allele. Other mutations of the insulin receptor gene may lead to insulin-resistance. While these results are still unclear, it suggests that the two disorders may be related. In the long run, insulin resistance may lead to type 2 diabetes.
Professor Roy Taylor’s work at Newcastle Universit
Recent studies have shown that people with type 2 diabetes are at a much higher risk of developing eye problems, and a leading Newcastle University researcher is looking into ways to prevent and treat diabetes. Professor Roy Taylor’s work has already helped reduce the number of people with diabetes in the UK. In fact, his work has improved the way people with diabetes can detect eye problems early. Professor Taylor’s research is widely accepted by the medical community, and he regularly gives invited lectures around the world.
The study also revealed that a high-protein diet helps people with diabetes reverse their condition. By removing fat from the body, insulin production returns to normal, and patients can achieve remission from the disease. This is an important development for those with type 2 diabetes, who often turn to surgery and medication. Ultimately, the research outlined in this book could lead to new treatments for the disease. But how will these changes affect people with type 2 diabetes?
Although the cause of Type 2 diabetes remains obscure, Professor Taylor’s research confirms the Twin Cycle Hypothesis – that excess fat causes the disease and is reversible. Previous Newcastle studies – funded by Diabetes UK – also indicated that the disease is reversible. The DiRECT trial at Newcastle University, for example, showed that patients can achieve remission of Type 2 diabetes in obese people by reducing their calorie intake.
Peter Attia’s TED talk on insulin resistance
In a TED talk in 2013, Peter Attia proposed that a low-carbohydrate diet might be useful in treating obesity. His ambitious and daring plan to combat the obesity epidemic was based on a wild leap. But Attia needed money to prove that his plan actually worked. And, what’s more, it’s still controversial.
After three years of living with Type 2 diabetes, Attia started to gain weight and was diagnosed with metabolic syndrome, a condition that occurs when a person becomes insulin resistant. After his diagnosis, Attia began questioning many of his assumptions about obesity and diabetes. Rather than looking at obesity as a symptom of diabetes, he wondered whether obesity caused insulin resistance and vice versa.
In his TED talk on insulin resistance and weight gain, Dr. Attia explained that this syndrome, also known as metabolic syndrome, is a symptom of insulin resistance. In fact, it’s a common part of chronic diseases such as diabetes, such as rheumatoid arthritis, and it may even lead to obesity. While it is not a cure for obesity, it can help patients who are struggling with diabetes and insulin resistance.
Professor Roger Unger’s prize-winning lecture
In 1964, Dr. Unger received the Lilly Award of the American Diabetes Association, the highest honor bestowed on researchers in the field. He was later elected to the National Academy of Sciences and the American Academy of Arts and Sciences. In 1980, he was awarded the Fred Conrad Koch Award, as well as the Rolf Luft Prize of the Karolinska Institutet in Stockholm. Dr. Unger’s research helped define the relationships between obesity, diabetes, and metabolic syndrome. His research also made UT Southwestern a world leader in the field of endocrinology.
Dr. Unger’s prize-winning lecture reveals a novel and potentially controversial theory about the relationship between insulin resistance and weight gain. Researchers have found that obesity increases the production of the pancreatic hormone glucagon, which causes insulin resistance in beta cells. Insulin resistance results in prolonged increases in blood glucose levels. Because of this, insulin-resistant people are more likely to develop type 2 diabetes.
Dr Kendrick and the extreme exceptions
Dr Malcom Kendrick’s theory of type 2 diabetes and the role of insulin resistance in causing weight gain is true with some exceptions. Generally speaking, the more carbohydrates we consume, the more insulin we produce, and the more weight we gain. While hyperinsulinemia is a complex disease and can be attributed to several causes, the obesity epidemic is primarily due to insulin resistance.
Insulin Resistance Cause Weight Gain – The Bottom Line
The relationship between insulin resistance and weight gain is complicated. While the exact cause is unclear, insulin resistance is associated with various ailments, including heart disease, diabetes, and obesity. It’s important to identify the early signs of insulin resistance, such as extra weight around the middle. High triglycerides and low HDL cholesterol are also risk factors. A high A1C level and low HDL cholesterol are also indicators of insulin resistance.
When the insulin level is too high, fat accumulates in the liver. This increases the export of ‘VLDL’ (a precursor of LDL ‘cholesterol’) into the blood. As the body fat builds up in the liver, the pancreas’ beta cells become impaired, and insulin levels in the blood rise rapidly. Insulin resistance leads to elevated levels of blood glucose and fat storage.
This result was not consistent between men and women. In women, insulin resistance was more than two times higher than that of noninsulin-resistant women. Researchers attributed the association to visceral fat. While the association between insulin resistance and weight gain was not remarkably strong, it’s worth highlighting the relationship between insulin resistance and weight gain in the long-term. If you have a family history of insulin resistance, this relationship may be particularly compelling.